Cefazolin

$60$66

Products Details

Product Description

– Cefazolin (Cephazolin) is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research[1]. Cefazolin has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD)[2].

Web ID

– HY-B1892

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C14H14N8O4S3

Citations

– mSystems. 2023 Dec 4:e0102623.|Nat Commun. 2022 Mar 2;13(1):1116.|ACS Omega. March 3, 2022.|Front Aging Neurosci. 2021 Oct 13;13:748637.|iScience. 5 January 2022, 103731.

References

– [1]R Quintiliani, et al. Cefazolin. Ann Intern Med. 1978 Nov;89(5 Pt 1):650-6.|[2]Peng Liang, et al. Perioperative use of cefazolin ameliorates postoperative cognitive dysfunction but induces gut inflammation in mice. J Neuroinflammation. 2018 Aug 22;15(1):235.|[3]Barbara Å»yżyÅ„ska-Granica, et al. The anti-inflammatory potential of cefazolin as common gamma chain cytokine inhibitor. Sci Rep. 2020 Feb 19;10(1):2886.

CAS Number

– 25953-19-9

Molecular Weight

– 454.51

Compound Purity

– 99.76

SMILES

– O=C(C(N12)=C(CSC3=NN=C(C)S3)CS[C@]2([H])[C@H](NC(CN4N=NN=C4)=O)C1=O)O

Clinical Information

– Launched

Research Area

– Infection; Inflammation/Immunology; Neurological Disease

Solubility

– DMSO : 250 mg/mL (ultrasonic)

Target

– Antibiotic;Bacterial

Isoform

– β-lactam

Pathway

– Anti-infection

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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