Ceapin-A7
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Ceapin-A7

SKU T9110-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 62 CAD through 683 CAD

Products Details

Product Description

– Ceapin-A7, with an IC50 of 0.59 μM, selectively inhibits ATF6α signaling in response to ER stress. This compound is instrumental in investigating ATF6α’s activation mechanism and its function in pathological conditions.

Web ID

– T9110

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H12F6N4O3

Citations

– 1. Zheng M, Zhai Y, Yu Y, et al.TNF compromises intestinal bile-acid tolerance dictating colitis progression and limited infliximab response.Cell Metabolism.2024

References

– Ciara M Gallagher, et al. Ceapins are a new class of unfolded protein response inhibitors, selectively targeting the ATF6α branch. eLife. 2016; 5: e11878.

CAS Number

– 2323027-38-7

Molecular Weight

– C20H12F6N4O3

Compound Purity

– 0.9974

SMILES

– FC(F)(F)c1ccc(Cn2cc(NC(=O)c3cc(on3)-c3ccco3)cn2)c(c1)C(F)(F)F

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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