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Ceapin-A7
$50 – $520
Products Details
Product Description
– Ceapin-A7 is a selective blocker of ATF6α signaling in response to ER stress, with an IC50 of 0.59 μM. Ceapin-A7 can be used to explore both the mechanism of activation of ATF6α and its role in pathological settings[1].
Web ID
– HY-108434
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C20H12F6N4O3
References
– [1]Ciara M Gallagher, et al. Ceapins are a new class of unfolded protein response inhibitors, selectively targeting the ATF6α branch. eLife. 2016; 5: e11878.
CAS Number
– 2323027-38-7
Molecular Weight
– 470.32
Compound Purity
– 99.15
SMILES
– O=C(NC1=CN(CC2=CC=C(C(F)(F)F)C=C2C(F)(F)F)N=C1)C3=NOC(C4=CC=CO4)=C3
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease; Neurological Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– ATF6
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
