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CE-245677
90 CAD – 1,075 CADPrice range: 90 CAD through 1,075 CAD
Products Details
Product Description
– CE-245677 is a potent, reversible inhibitor of Tie2 and TrkA/B kinases, with cellular IC50 values of 4.7 nM and 1 nM, respectively.
Web ID
– T14921
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H22Cl2N6O3
References
– Susan LaGreca, et al. Identification of selective, orally active Tie2 kinase inhibitors and discovery of CE-245,677 and PF-371,989. Cancer Research. AACR Annual Meeting-Apr 14-18, 2007.
CAS Number
– 717899-97-3
Molecular Weight
– C24H22Cl2N6O3
Compound Purity
– 0.9923
SMILES
– COc1ccc(cc1NC(=O)Nc1ccc(Cl)cc1Cl)C(=O)c1cn(C(C)C)c2ncnc(N)c12
Target
– Others
Pathway
– Tyrosine Kinase/Adaptors
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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