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Products Details
Product Description
– CDK9-IN-24 (compound 21a) is a highly selective CDK9 inhibitor with significant inhibitory effect on tumor growth. CDK9-IN-24 effectively blocks cell proliferation and induces apoptosis by downregulating Mcl-1 and c-Myc, and can be used in acute myeloid leukemia research[1].
Web ID
– HY-155153
Shipping
– Room temperature
Molecular Formula
– C27H31N3O4
References
– [1]Wu T, et al. Design and optimization of selective and potent CDK9 inhibitors with flavonoid scaffold for the treatment of acute myeloid leukemia. Eur J Med Chem. 2023 Nov 5;259:115711.
Molecular Weight
– 461.55
SMILES
– CN(CC1)CC=C1C2=C3C(C(C=C(C4=CC=C(N5CCN(C)CC5)C=C4)O3)=O)=C(O)C=C2OC
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– Apoptosis;CDK
Isoform
– CDK9
Pathway
– Apoptosis;Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
