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Products Details
Product Description
– CDK2-IN-9 is a potent CDK2 inhibitor with an IC50 of 0.63 µM. CDK2-IN-9 shows antiproliferative activity. CDK2-IN-9 induces apoptosis and cell cycle arrest at S and G2/M phase. CDK2-IN-9 has the potential for the research of melanoma[1].
Web ID
– HY-144811
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C21H16ClN3O4S
References
– [1]Mohammed ER, et al. Development of newly synthesised quinazolinone-based CDK2 inhibitors with potent efficacy against melanoma. J Enzyme Inhib Med Chem. 2022 Dec;37(1):686-700.
CAS Number
– 2919216-33-2
Molecular Weight
– 441.89
SMILES
– O=S(C1=CC=C(Cl)C=C1)(NN2C(COC3=CC=CC=C3)=NC4=C(C=CC=C4)C2=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;CDK
Isoform
– CDK2
Pathway
– Apoptosis;Cell Cycle/DNA Damage
Product type
– Reference compound
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