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Products Details
Product Description
– CDK2-IN-11 (compound 9d) is a potent CDK2 inhibitor with an IC50 of 6.4 μM, and KI values of 23.4 nM, 56.3 nM and 44.3 nM for hCA II, hCA IX and hCA XII, respectively. CDK2-IN-11 can be used for researching anticancer[1].
Web ID
– HY-150572
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C18H14ClN7O2S
References
– [1]Said MA, et al. Sulfonamide-based ring-fused analogues for CAN508 as novel carbonic anhydrase inhibitors endowed with antitumor activity: Design, synthesis, and in vitro biological evaluation. Eur J Med Chem. 2020 Mar 1;189:112019.
CAS Number
– 2410402-82-1
Molecular Weight
– 427.87
SMILES
– O=S(C1=CC=C(/N=N/C2=C3N=CC=C(C4=CC=C(Cl)C=C4)N3N=C2N)C=C1)(N)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Carbonic Anhydrase;CDK
Isoform
– CA â…¡;CA â…¨;CA XII
Pathway
– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
