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Products Details
Product Description
– CDK1-IN-4 (10d) is a selective CDK1 inhibitor with IC50s of 44.52, 624.93 and 135.22 nM for CDK1, CDK2 and CDK5, respectively. CDK1-IN4 inhibits the growth of cancer cells by affecting cell cycle. CDK1-IN-4 can be used for the research of cancer[1].
Web ID
– HY-151408
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C26H24ClN5S
References
– [1]Akl L, et al. Identification of novel piperazine-tethered phthalazines as selective CDK1 inhibitors endowed with in vitro anticancer activity toward the pancreatic cancer. Eur J Med Chem. 2022 Aug 31;243:114704.
Molecular Weight
– 474.02
SMILES
– S=C(N1CCN(C2=NN=C(CC3=CC=CC=C3)C4=C2C=CC=C4)CC1)NC5=CC=CC(Cl)=C5
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– CDK
Isoform
– CDK1;CDK2;CDK5
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
