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Products Details
Product Description
– CDK/HDAC-IN-1 shows remarkable CDK2/4/6 and HDAC6 inhibitory activity of IC50 = 60.9 ± 2.9, 276 ± 22.3, 27.2 ± 4.2, and 128.6 ± 0.4 nM, respectively.
Web ID
– HY-132914
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C20H18N4O4
References
– [1]Cao Z, et al. Indirubin Derivatives as Dual Inhibitors Targeting Cyclin-Dependent Kinase and Histone Deacetylase for Treating Cancer. J Med Chem. 2021 Oct 28;64(20):15280-15296.
CAS Number
– 2762181-73-5
Molecular Weight
– 378.38
SMILES
– O=C(/C1=C2NC3=CC=CC=C3C2=N/OCCCC(NO)=O)NC4=C1C=CC=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– CDK
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
