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Cdc7-IN-1
$350 – $2,250
Products Details
Product Description
– Cdc7-IN-1 (Compound 13) is a highly potent, selective and ATP competitive inhibitor of Cdc7 kinase, with an IC50 value of 0.6 nM at 1 mM ATP and with slow off-rate characteristics. Cdc7-IN-1 potently inhibits Cdc7 activity in cancer cells, and effectively induces cell death[1].
Web ID
– HY-101523
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C21H16ClN3O4
References
– [1]Irie T, et al. Discovery of novel furanone derivatives as potent Cdc7 kinase inhibitors. Eur J Med Chem. 2017 Apr 21;130:406-418.
CAS Number
– 1402055-25-7
Molecular Weight
– 409.82
Compound Purity
– 99.77
SMILES
– O=C1C(C(OCC)=O)=C(NC2=C(Cl)C=CC=C2)O/C1=CC3=CNC4=C3C=CC=N4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 5.2 mg/mL (ultrasonic)
Target
– CDK
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
