Download Files:
CD437
$70 – $620
Products Details
Product Description
– CD437 is a selective Retinoic Acid Receptor γ (RARγ) agonist.
Web ID
– HY-100532
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C27H26O3
References
– [1]Li Y, et al. Molecular determinants of AHPN (CD437)-induced growth arrest and apoptosis in human lung cancer cell lines. Mol Cell Biol. 1998 Aug;18(8):4719-31.|[2]Schadendorf D, et al. Treatment of melanoma cells with the synthetic retinoid CD437 induces apoptosis via activation of AP-1 in vitro, and causes growth inhibition in xenografts in vivo. J Cell Biol. 1996 Dec;135(6 Pt 2):1889-98.
CAS Number
– 125316-60-1
Molecular Weight
– 398.49
Compound Purity
– 98.0
SMILES
– O=C(C1=CC=C2C=C(C3=CC=C(O)C(C4(C5)CC6CC5CC(C6)C4)=C3)C=CC2=C1)O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 150 mg/mL (ultrasonic;warming)
Target
– Autophagy;RAR/RXR
Pathway
– Autophagy;Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
