CCT196969

SKU HY-12846-10 mg Category Tags , ,

$84$672

Products Details

Product Description

– CCT196969 is a pan-Raf inhibitor, which inhibits B-Raf, BRafV600E and CRAF with IC50s of 0.1, 0.04, and 0.01 μM, respectively.

Web ID

– HY-12846

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C27H24FN7O3

References

– [1]Girotti MR, et al. Paradox-breaking RAF inhibitors that also target SRC are effective in drug-resistant BRAF mutant melanoma. Cancer Cell. 2015 Jan 12;27(1):85-96.

CAS Number

– 1163719-56-9

Molecular Weight

– 513.52

Compound Purity

– 99.63

SMILES

– O=C1NC2=NC=CC(OC3=CC=C(NC(NC4=CC(C(C)(C)C)=NN4C5=CC=CC=C5)=O)C(F)=C3)=C2N=C1

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : ≥ 32 mg/mL

Target

– Raf

Isoform

– BRaf;c-Raf

Pathway

– MAPK/ERK Pathway

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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