CCR8 antagonist 2

$350$2,850

Products Details

Product Description

– CCR8 antagonist 2 is a potent antagonist of CCR8. CCR8 (C-C Motif Chemokine Receptor 8) is predominantly expressed on Treg cells and Th2 cells, but not on Th1 cells. CCR8 antagonist 2 inhibits CCR8 activity, which may be used in the research of diseases mediated by CCR8, such as cancer, and/or neuropathic pain (extracted from patent WO2022000443A1, compound 220)[1].

Web ID

– HY-144200

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture and light)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C23H30ClN3O3S

References

– [1]Guohuang FAN, et al. Methods and compositions for targeting tregs using ccr8 inhibitors.

CAS Number

– 2756350-98-6

Molecular Weight

– 464.02

Compound Purity

– 99.71

SMILES

– O=C(NC1=C(C)C=C(S(=O)(N[C@@H](C2CCN(C)CC2)C)=O)C=C1Cl)C3=CC=CC=C3C

Clinical Information

– No Development Reported

Research Area

– Cancer; Neurological Disease

Solubility

– DMSO : 4 mg/mL (ultrasonic;warming;heat to 60°C)

Target

– CCR

Isoform

– CCR8

Pathway

– GPCR/G Protein;Immunology/Inflammation

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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