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CCR8 antagonist 1
SKU
HY-144197-10 mg
Category Reference compound
Tags CCR, GPCR/G Protein;Immunology/Inflammation, Infection; Inflammation/Immunology
$260 – $2,100
Products Details
Product Description
– CCR8 antagonist 1 (compound 15) is a potente human CCR8 antagonist with a Ki of 1.6 nM[1].
Web ID
– HY-144197
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C26H29N3O5S
References
– [1]Jenkins TJ, et al. Design, synthesis, and evaluation of naphthalene-sulfonamide antagonists of human CCR8. J Med Chem. 2007;50(3):566-584.
CAS Number
– 723304-76-5
Molecular Weight
– 495.59
Compound Purity
– 98.71
SMILES
– O=C(N1CCC(NS(=O)(C2=C3C=CC=CC3=C(NC(C4=CC=CC=C4C)=O)C=C2)=O)CC1)OCC
Clinical Information
– No Development Reported
Research Area
– Infection; Inflammation/Immunology
Solubility
– DMSO : 25 mg/mL (ultrasonic)
Target
– CCR
Isoform
– CCR8
Pathway
– GPCR/G Protein;Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.