CCR2 antagonist 4

SKU T13114-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 77 CAD through 1,173 CAD

Products Details

Product Description

– CCR2 antagonist 4 (Teijin compound 1) is a potent and specific CCR2 antagonist with IC50 values of 180 nM and 24 nM for CCR2 inhibition and MCP-1-induced chemotaxis inhibition, respectively.

Web ID

– T13114

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H21ClF3N3O2

References

– Moree WJ, et al. Potent antagonists of the CCR2b receptor. Part 3: SAR of the (R)-3-aminopyrrolidine series. Bioorg Med Chem Lett. 2008 Mar 15;18(6):1869-73.

CAS Number

– 226226-39-7

Molecular Weight

– C21H21ClF3N3O2

Compound Purity

– 0.9963

SMILES

– FC(F)(F)c1cccc(c1)C(=O)NCC(=O)N[C@@H]1CCN(Cc2ccc(Cl)cc2)C1

Target

– Others

Pathway

– Microbiology/Virology|||Immunology/Inflammation|||GPCR/G Protein

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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