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CCR1 antagonist 9
SKU
HY-124759-10 mg
Category Reference compound
Tags CCR, GPCR/G Protein;Immunology/Inflammation, Inflammation/Immunology
$300 – $1,950
Products Details
Product Description
– CCR1 antagonist 9 is a potent and selective CCR1 antagonist with an IC50 of 6.8 nM in calcium flux assay[1].
Web ID
– HY-124759
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C20H16FN5O3S
References
– [1]Harcken C, et al. Identification of novel azaindazole CCR1 antagonist clinical candidates. Bioorg Med Chem Lett. 2019 Feb 1;29(3):441-448.
CAS Number
– 1220026-26-5
Molecular Weight
– 425.44
Compound Purity
– 99.93
SMILES
– O=C(C1=CN=CC2=C1C=NN2C3=CC=C(F)C=C3)NCC4=CC(S(=O)(C)=O)=NC=C4
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 83.33 mg/mL (ultrasonic)
Target
– CCR
Isoform
– CCR1
Pathway
– GPCR/G Protein;Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.