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Products Details
Product Description
– CCG-257081 (MRTF/SRF-IN-1) is an inhibitor of cardiac myosin-related transcription factor and serum response factor (MRTF/SRF) that acts by inhibiting the Rho/MRTF/SRF pathway.CCG-257081 has shown efficacy in preventing bleomycin-induced fibrosis in several mouse models. CCG-257081 can be used in cancer prevention and fibrosis research.
Web ID
– T30778
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H19ClF3N3O2
References
– Larsen Scott D, et al. Preparation of substituted piperidine-3-carboxamides as inhibitors of myocardin-related transcription factor and serum response factor (MTRF/SRF)-mediated gene transcription. WO2016073847 A2.
CAS Number
– 1922098-90-5
Molecular Weight
– C24H19ClF3N3O2
Compound Purity
– 0.9992
SMILES
– C(=O)(C=1C=C(C=C(F)C1)C=2C=CN=CC2)N3CC(C(NC4=CC=C(Cl)C=C4)=O)CC(F)(F)C3
Pathway
– Cell Cycle/Checkpoint|||MAPK|||GPCR/G Protein
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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