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Products Details
Product Description
– CCG-232964 is an orally active inhibitor of Rho/MRTF/SRF. CCG-232964 inhibits LPA-induced CTGF gene expression[1].
Web ID
– HY-130011
Shipping
– Room temperature
Molecular Formula
– C15H15ClN2O3S
References
– [1]Kahl, Dylan, et al. 5-Aryl-1,3,4-oxadiazol-2-ylthioalkanoic Acids: A Highly Potent New Class of Inhibitors of Rho/Myocardin-Related Transcription Factor (MRTF)/Serum Reponse Factor (SRF)-Mediated Gene Transcription as Potential Antifibrotic Agents for Scleroderma. Journal of Medicinal Chemistry, (), acs.jmedchem.8b01772–.
CAS Number
– 2349373-70-0
Molecular Weight
– 338.81
SMILES
– O=C(O)CCCSC1=NN=C(C2=CC=C(C3CC3)C=C2Cl)O1
Clinical Information
– No Development Reported
Research Area
– Cancer; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Ras;ROCK
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton;GPCR/G Protein;Stem Cell/Wnt;TGF-beta/Smad
Product type
– Reference compound
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