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CC-885

$150$1,000

Products Details

Product Description

– CC-885 is a cereblon (CRBN) modulator with potent anti-tumour activity.

Web ID

– HY-101488

Storage Temperature

– -20°C, 3 years (Powder)

Shipping

– Blue Ice

Applications

– Cancer-programmed cell death

Molecular Formula

– C22H21ClN4O4

References

– [1]Mary E. Matyskiela, et al. A novel cereblon modulator recruits GSPT1 to the CRL4CRBN ubiquitin ligase. Nature. 2016 Jul 14;535(7611):252-7.

CAS Number

– 1010100-07-8

Molecular Weight

– 440.88

Compound Purity

– 99.85

SMILES

– O=C(NCC1=CC2=C(C(N(C(CC3)C(NC3=O)=O)C2)=O)C=C1)NC4=CC=C(C)C(Cl)=C4

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 67.5 mg/mL (ultrasonic)

Target

– Ligands for E3 Ligase;Molecular Glues

Pathway

– PROTAC

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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