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CC-885
SKU
HY-101488-10 mg
Category Reference compound
Tags Cancer, Ligands for E3 Ligase;Molecular Glues, PROTAC
$150 – $1,000
Products Details
Product Description
– CC-885 is a cereblon (CRBN) modulator with potent anti-tumour activity.
Web ID
– HY-101488
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C22H21ClN4O4
References
– [1]Mary E. Matyskiela, et al. A novel cereblon modulator recruits GSPT1 to the CRL4CRBN ubiquitin ligase. Nature. 2016 Jul 14;535(7611):252-7.
CAS Number
– 1010100-07-8
Molecular Weight
– 440.88
Compound Purity
– 99.85
SMILES
– O=C(NCC1=CC2=C(C(N(C(CC3)C(NC3=O)=O)C2)=O)C=C1)NC4=CC=C(C)C(Cl)=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 67.5 mg/mL (ultrasonic)
Target
– Ligands for E3 Ligase;Molecular Glues
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.