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Products Details
Product Description
– Cbl-b-IN-7 (Compound 248) is a casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl inhibitor with IC50s of 6.7 nM and 5.2 nM, respectively[1].
Web ID
– HY-156763
Shipping
– Room temperature
Molecular Formula
– C29H31F4N5O2
References
– [1]Jun Liang, et al. Lactams as cbl-b inhibitors. Patent WO2022169997A1.
CAS Number
– 2815221-35-1
Molecular Weight
– 557.58
SMILES
– F[C@@H](C1=NN=CN1C)C2(C3=CC(N4CC5=C(C(F)(F)F)C=C([C@H](C)NC6(CCC6)C)C=C5C4=O)=CC=C3)COC2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– E1/E2/E3 Enzyme
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
