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Products Details
Product Description
– Cbl-b-IN-13 (Example 520) is a Cbl-b inhibitor with an IC50 of <100 nM. Cbl-b-IN-13 has the ability to activate T-cells[1].
Web ID
– HY-156769
Shipping
– Room temperature
Molecular Formula
– C29H30F3N5O2
References
– [1]Paul A. Barsanti, et al. Inhibitors of cbl-b and methods of use thereof. Patent WO2019148005A1.
CAS Number
– 2368841-85-2
Molecular Weight
– 537.58
SMILES
– O=C1C2=CC(CN3CCC4(CC4)C3)=CC(C(F)(F)F)=C2CN1C5=CC=CC(C6(CC7=NN=CN7C)COC6)=C5
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– E1/E2/E3 Enzyme
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
