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CAY10580
$680
Only 1000 item(s) left in stock.
Products Details
Product Description
– CAY10580 is a potent and selective prostaglandin EP4 receptor agonist (Ki=35 nM)[1].
Web ID
– HY-135259
Storage Temperature
– Solution, -20°C, 2 years
Shipping
– Blue Ice
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C19H35NO4
References
– [1]Billot X, et al. Discovery of a potent and selective agonist of the prostaglandin EP4 receptor. Bioorg Med Chem Lett. 2003;13(6):1129-1132. |[2]Olesen ET, et al. Vasopressin-independent targeting of aquaporin-2 by selective E-prostanoid receptor agonists alleviates nephrogenic diabetes insipidus. Proc Natl Acad Sci U S A. 2011;108(31):12949-12954. |[3]Ying F, et al. EP4 emerges as a novel regulator of bile acid synthesis and its activation protects against hypercholesterolemia. Biochim Biophys Acta Mol Cell Biol Lipids. 2018;1863(9):1029-1040.
CAS Number
– 64054-40-6
Molecular Weight
– 341.49
Compound Purity
– 97.0
SMILES
– O=C(O)CCCCCCN1C(CCC(O)CCCCC)CCC1=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Prostaglandin Receptor
Isoform
– EP
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
