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Products Details
Product Description
– Cathepsin L/S-IN-1 is a dual inhibitor of Cathepsin L and Cathepsin S with IC50s of 4.10 μM and 1.79 μM, respectively. Cathepsin L/S-IN-1 shows a significant antimetastatic and invasive effects on pancreatic cancer BxPC-3 and PANC-1 cells[1].
Web ID
– HY-152204
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C29H33BrN4O4S
References
– [1]Huang H, et al. Design and synthesis of dual cathepsin L and S inhibitors and antimetastatic activity evaluation in pancreatic cancer cells. Bioorg Med Chem Lett. 2022 Nov 23;80:129087.
Molecular Weight
– 613.57
SMILES
– O[C@@H](COC[C@H](NS(=O)(C1=CC=C(C=C1)Br)=O)CC2=CC=CC=C2)CN(CC3)CCN3C(C=CC=C4)=C4C#N
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Cathepsin
Isoform
– Cathepsin L;Cathepsin S
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
