Download Files:
(+)-Catechin hydrate
$50
Only 1000 item(s) left in stock.
Products Details
Product Description
– (+)-Catechin hydrate inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.
Web ID
– HY-N0355
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C15H14O6.xH2O
Citations
– Autophagy. 2021 Apr;17(4):872-887.|Acta Pharm Sin B. 2021 Jan;11(1):143-155.|Biochem Biophys Res Commun. 2018 Sep 3;503(1):297-303.|Biochem Biophys Res Commun. 2023 Dec 20, 687, 149196.|Biomaterials. 2021, 120952.|Int J Insect Sci. 2018 Feb 28;10:1179543318758409.|Plant Cell Physiol. 2020 Feb 1;61(2):318-330.|Plants. 2021, 10(11), 2525.|SSRN. 2023 Jul 14.
References
– [1]Waffo-Téguo P, et al. Potential cancer-chemopreventive activities of wine stilbenoids and flavans extracted from grape (Vitis vinifera) cell cultures. Nutr Cancer. 2001;40(2):173-9.|[2]Alshatwi AA. Catechin hydrate suppresses MCF-7 proliferation through TP53/Caspase-mediated apoptosis. J Exp Clin Cancer Res. 2010 Dec 17;29:167.|[3]Cheruku SP, et al. Catechin ameliorates doxorubicin-induced neuronal cytotoxicity in in vitro and episodic memory deficit in in vivo in Wistar rats. Cytotechnology. 2018 Feb;70(1):245-259.
CAS Number
– 225937-10-0
Molecular Weight
– N/A
Compound Purity
– 99.59
SMILES
– OC1=CC(O)=C(C[C@H](O)[C@@H](C2=CC=C(O)C(O)=C2)O3)C3=C1.[xH2O]
Clinical Information
– Launched
Research Area
– Cancer
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– COX
Isoform
– COX-1
Pathway
– Immunology/Inflammation
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
