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Products Details
Product Description
– CaSR
antagonist-1 is a calcium sensing receptor (CaSR) antagonist
with an IC50 value of 50 nM. CaSR
antagonist-1 can be used for the research of disorders associated with abnormal
bone or mineral homeostasis such as osteoporosis[1].
Web ID
– HY-153258
Shipping
– Room temperature
Molecular Formula
– C29H24FN3O2S
References
– [1]Ramanjulu JM, et al. Overcoming the Pregnane X
Receptor Liability: Rational Design to Eliminate PXR-Mediated CYP Induction.
ACS Med Chem Lett. 2021 Aug 10;12(9):1396-1404.
CAS Number
– 1219811-83-2
Molecular Weight
– 497.58
SMILES
– O=C1C(C2=CC(C3=CC=CC=N3)=C(C)S2)=C(C)N=C(N1CCC4=CC=CC=C4)C5=C(O)C(F)=CC=C5
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– CaSR
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
