Products Details

Product Description

– Casein kinase 1δ-IN-6 is a potent and selective protein kinase CK-1δ inhibitor with an IC50 of 23 nM. Casein kinase 1δ-IN-6 shows neuroprotective and anti-inflammatory properties both in vitro and in vivo. Casein kinase 1δ-IN-6 is a promising drug candidate and can be used for neurodegenerative diseases research.

Web ID

– HY-153905

Shipping

– Room temperature

Molecular Formula

– C16H10ClF3N2OS

References

– [1]José A Morales-Garcia, et al. Biological and Pharmacological Characterization of Benzothiazole-Based CK-1δ Inhibitors in Models of Parkinson’s Disease. ACS Omega. 2017 Aug 31;2(8):5215-5220.

CAS Number

– 1579991-01-7

Molecular Weight

– 370.78

SMILES

– O=C(CC1=CC(Cl)=CC=C1)NC2=NC3=C(S2)C=C(C(F)(F)F)C=C3

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Casein Kinase

Pathway

– Cell Cycle/DNA Damage;Stem Cell/Wnt

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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