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Carubicin
Products Details
Product Description
– Carubicin (Carminomycin) is a microbially-derived compound. Carubicin is an effective inhibitor of VHL-defective (VHL−/−) CCRCC cell proliferation. Carubicin also induces apoptosis by a mechanism independent of p53 or hypoxia-inducible factor HIF2. Carubicin has the potential for the research of cancer diseases[1][2].
Web ID
– HY-B2171
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C26H27NO10
References
– [1][1]Woldemichael GM, et al. Carminomycin I is an apoptosis inducer that targets the Golgi complex in clear cell renal carcinoma cells. Cancer Res. 2011 Jan 1;71(1):134-42.
CAS Number
– 50935-04-1
Molecular Weight
– 513.49
SMILES
– OC1=C2C(C(C3=C(O)C=CC=C3C2=O)=O)=C(O)C([C@H]4O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O)N)=C1C[C@](O)(C4)C(C)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection
Solubility
– 10 mM in DMSO
Target
– Apoptosis
Pathway
– Apoptosis
Product type
– Natural Products
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