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CARM1-IN-3 (dihydrochloride)
$450 – $2,300
Products Details
Product Description
– CARM1-IN-3 dihydrochloride (compound 17b) is a potent and selective co-activator associated arginine methyltransferase (CARM1) inhibitor with IC50 values of 0.07, >25 µM for CARM1 and CARM3, respectively[1].
Web ID
– HY-15214A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C24H34Cl2N4O2
References
– [1]Wan H, et al. Benzo[d]imidazole inhibitors of Coactivator Associated Arginine Methyltransferase 1 (CARM1)–Hit to Lead studies. Bioorg Med Chem Lett. 2009 Sep 1;19(17):5063-6.
Molecular Weight
– 481.46
Compound Purity
– 98.77
SMILES
– CNCCN1CCC(C2=CC3=C(N=C(C4=C(OC)C=CC=C4OC)N3)C(C)=C2)CC1.Cl.Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Histone Methyltransferase
Isoform
– PRMT4
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
