Carboxyamidotriazole Orotate

SKU T14871-1 mg Category Brand:

Price range: 53 CAD through 910 CAD

Products Details

Product Description

– Carboxyamidotriazole Orotate (L-651582 Orotate) is a cytostatic inhibitor of non-voltage-operated calcium channels and associated signaling pathways. As the orotate salt form of Carboxyamidotriazole (CAI), it is an orally bioavailable signal transduction inhibitor with in vitro antileukaemic activity, exhibiting anti-tumor, anti-inflammatory, and antiangiogenic effects.

Web ID

– T14871

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H16Cl3N7O6

References

– Corrado C, et al. Carboxyamidotriazole-orotate inhibits the growth of imatinib-resistant chronic myeloid leukaemia cells and modulates exosomes-stimulated angiogenesis. PLoS One. 2012;7(8):e42310.

CAS Number

– 187739-60-2

Molecular Weight

– C22H16Cl3N7O6

Compound Purity

– 0.9988

SMILES

– OC(=O)c1cc(=O)[nH]c(=O)[nH]1.NC(=O)c1nnn(Cc2cc(Cl)c(C(=O)c3ccc(Cl)cc3)c(Cl)c2)c1N

Target

– Others

Pathway

– Membrane transporter/Ion channel|||Metabolism

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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