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Products Details
Product Description
– Carbonic anhydrase inhibitor 7 (compound 5b) is a potent inhibitor of human carbonic anhydrase (hCA), with Kis of 6.5 nM, 7.1 nM, 72.1 nM, and 255.8 nM for hCA IX, hCA II, hCA XII and hCA I, respectively[1].
Web ID
– HY-144641
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C23H17N3O5S
References
– [1]Swain B, et, al. Exploration of 2-phenylquinoline-4-carboxamide linked benzene sulfonamide derivatives as isoform selective inhibitors of transmembrane human carbonic anhydrases. Eur J Med Chem. 2022 Apr 15;234:114247.
CAS Number
– 546105-61-7
Molecular Weight
– 447.46
SMILES
– O=C(C1=CC(C2=CC=C(OCO3)C3=C2)=NC4=CC=CC=C14)NC5=CC=C(S(=O)(N)=O)C=C5
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Carbonic Anhydrase
Isoform
– CA â…¡;CA â…¨;CA XII
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
