Carbonic anhydrase inhibitor 11

SKU HY-115998-Get quote Category Tags , ,

Products Details

Product Description

– Carbonic anhydrase inhibitor 11 (compound VI) is a potent, selective carbonic anhydrase inhibitor. Carbonic anhydrase inhibitor 11 shows Ki values of 40, 39, 200 and 900 nM against CA II, IX, and XII, respectively[1].

Web ID

– HY-115998

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C19H15F3N4O3S2

References

– [1]Abdel-Mohsen HT, et al. Application of the dual-tail approach for the design and synthesis of novel Thiopyrimidine-Benzenesulfonamide hybrids as selective carbonic anhydrase inhibitors. Eur J Med Chem. 2022;228:114004.

CAS Number

– 2411059-71-5

Molecular Weight

– 468.47

SMILES

– O=S(C1=CC=C(NC2=NC(SCC(C3=CC=C(C(F)(F)F)C=C3)=O)=NC=C2)C=C1)(N)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Carbonic Anhydrase

Isoform

– CA â…¡

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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