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Products Details
Product Description
– Carbonic anhydrase inhibitor 11 (compound VI) is a potent, selective carbonic anhydrase inhibitor. Carbonic anhydrase inhibitor 11 shows Ki values of 40, 39, 200 and 900 nM against CA II, IX, and XII, respectively[1].
Web ID
– HY-115998
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C19H15F3N4O3S2
References
– [1]Abdel-Mohsen HT, et al. Application of the dual-tail approach for the design and synthesis of novel Thiopyrimidine-Benzenesulfonamide hybrids as selective carbonic anhydrase inhibitors. Eur J Med Chem. 2022;228:114004.
CAS Number
– 2411059-71-5
Molecular Weight
– 468.47
SMILES
– O=S(C1=CC=C(NC2=NC(SCC(C3=CC=C(C(F)(F)F)C=C3)=O)=NC=C2)C=C1)(N)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Carbonic Anhydrase
Isoform
– CA Ⅱ
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
