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Product Description
– Carbonic anhydrase inhibitor 10 is a potent hCA IX inhibitor with a Ki value of 6.2 nM. Carbonic anhydrase inhibitor 10 exhibits anti-proliferative activity against MCF-7 cancer cell line with an IC50 of 11.9 μM. Carbonic anhydrase inhibitor 10 can be used for cancer research[1].
Web ID
– HY-115994
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C14H17N5O3S
References
– [1]Diaaeldin M Elimam, et al. Natural inspired ligustrazine-based SLC-0111 analogues as novel carbonic anhydrase inhibitors. Eur J Med Chem. 2022 Jan 15;228:114008.
CAS Number
– 2883453-30-1
Molecular Weight
– 335.38
SMILES
– CC1=NC(C)=C(N=C1NC(NC2=CC=C(C=C2)S(N)(=O)=O)=O)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Carbonic Anhydrase
Isoform
– CA â…¨
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
