Carbonic anhydrase inhibitor 10

SKU HY-115994-Get quote Category Tags , ,

Products Details

Product Description

– Carbonic anhydrase inhibitor 10 is a potent hCA IX inhibitor with a Ki value of 6.2 nM. Carbonic anhydrase inhibitor 10 exhibits anti-proliferative activity against MCF-7 cancer cell line with an IC50 of 11.9 μM. Carbonic anhydrase inhibitor 10 can be used for cancer research[1].

Web ID

– HY-115994

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C14H17N5O3S

References

– [1]Diaaeldin M Elimam, et al. Natural inspired ligustrazine-based SLC-0111 analogues as novel carbonic anhydrase inhibitors. Eur J Med Chem. 2022 Jan 15;228:114008.

CAS Number

– 2883453-30-1

Molecular Weight

– 335.38

SMILES

– CC1=NC(C)=C(N=C1NC(NC2=CC=C(C=C2)S(N)(=O)=O)=O)C

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Carbonic Anhydrase

Isoform

– CA Ⅸ

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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