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Cap-dependent endonuclease-IN-9
Products Details
Product Description
– Cap-dependent endonuclease-IN-9 is a potent inhibitor of cap-dependent endonuclease (CEN). Not only can Cap-dependent endonuclease-IN-9 inhibit influenza virus well, but also has lower cytotoxicity, better in vivo agent kinetic properties and in vivo pharmacodynamic properties. Cap-dependent endonuclease-IN-9 has strong inhibitory effect on RNA polymerase activity of A virus (extracted from patent CN112521386A, compound VI-1)[1].
Web ID
– HY-143755
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C29H22F2N4O7S
References
– [1]Yutian Zhou, et al. Polycyclic pyridone compounds with antiviral effects and their pharmaceutical compositions and uses. Patent CN112521386A.
CAS Number
– 2631005-84-8
Molecular Weight
– 608.57
SMILES
– O=C1N2[C@@H](CC3=C(N=CO3)C2)N([C@H]4C5=CC=C(F)C(F)=C5CSC6=CC=CC=C64)N7C1=C(C(C=C7)=O)OCOC(OC)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Influenza Virus
Pathway
– Anti-infection
Product type
– Reference compound
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