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Canagliflozin (hemihydrate)
$50 – $150
Products Details
Product Description
– Canagliflozin hemihydrate (JNJ28431754 hemihydrate) is a selective SGLT2 inhibitor with IC50s of 2 nM, 3.7 nM, and 4.4 nM for mSGLT2, rSGLT2, and hSGLT2 in CHOK cells, respectively[1].
Web ID
– HY-I0383
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C24H26FO5.5S
References
– [1]Liang Y, et al.
Effect of canagliflozin on renal threshold for glucose, glycemia, and body weight in normal and diabetic animal models.
PLoS One. 2012;7(2):e30555.
CAS Number
– 928672-86-0
Molecular Weight
– 453.52
Compound Purity
– 99.95
SMILES
– CC1=CC=C([C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2)C=C1CC3=CC=C(C4=CC=C(F)C=C4)S3.[0.5H2O]
Clinical Information
– Launched
Research Area
– Cancer; Metabolic Disease
Solubility
– DMSO : ≥ 100 mg/mL
Target
– SGLT
Isoform
– SGLT2
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
