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Calcitriol Derivatives
SKU
HY-76802-Get quote
Category Reference compound
Tags Metabolic Disease, VD/VDR, Vitamin D Related/Nuclear Receptor
Web ID
– HY-76802
Shipping
– Room temperature
Molecular Formula
– C30H47NO3
References
– [1]Barrera D, Noyola-MartÃnez N, Avila E, Halhali A, Larrea F, DÃaz L.
Calcitriol inhibits interleukin-10 expression in cultured human trophoblasts under normal and inflammatory conditions.
Cytokine. 2012 Mar;57(3):316-21.|[2]Lydia A, Asanuma K, Nonaka K, Takagi M, Jeong KH, Kodama F, Asao R, Asanuma E, Prodjosudjadi W, Tomino Y.
Effects of 22-oxa-calcitriol on podocyte injury in adriamycin-induced nephrosis.
Am J Nephrol. 2012;35(1):58-68.|[3]Michalak K, Wicha J.
Total synthesis of a CD-ring: side-chain building block for preparing 17-epi-calcitriol derivatives from the Hajos-Parrish dione.
J Org Chem. 2011 Aug 19;76(16):6906-11.|[4]Moorthi RN, Kandula P, Moe SM.
Optimal vitamin D, calcitriol, and vitamin D analog replacement in chronic kidney disease: to D or not to D: that is the question.
Curr Opin Nephrol Hypertens. 2011 Jul;20(4):354-9.|[5]Yu WD, Ma Y, Flynn G, Muindi JR, Kong RX, Trump DL, Johnson CS.
Calcitriol enhances gemcitabine anti-tumor activity in vitro and in vivo by promoting apoptosis in a human pancreatic carcinoma model system.
Cell Cycle. 2010 Aug 1;9(15):3022-9.
CAS Number
– 2070009-24-2
Molecular Weight
– 469.70
SMILES
– O[C@H](C/1=C)C[C@@H](CC1=CC=C2[C@@](CC[C@@H]3[C@@H](CCCC(C)(O)C)C)([H])[C@]3(C)CCC2)OCCC#N
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– VD/VDR
Pathway
– Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.