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Calcifediol
$57 – $980
Products Details
Product Description
– Calcifediol (25-hydroxy Vitamin D3), a major circulating metabolite of vitamin D3, is a potent VDR inhibitor[1][2].
Web ID
– HY-32351
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C27H44O2
Citations
– Front Pharmacol. 2020 Mar 31;11:200.|Int Immunopharmacol. 2023 Jun 30;122:110558.|Int J Mol Sci. 2017 Dec 19;18(12). pii: E2764.|Nat Chem Biol. 2022 Aug 18.|Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2117004119.|Ther Adv Endocrinol. 2020 Oct 20. |Sci Rep. 2022 Feb 22;12(1):3014.
References
– [1]Castoldi A, et al. Calcifediol-loaded liposomes for local treatment of pulmonary bacterial infections. Eur J Pharm Biopharm. 2016 Nov 22.|[2]Wei Zheng, et al. Vitamin D-induced vitamin D receptor expression induces tamoxifen sensitivity in MCF-7 stem cells via suppression of Wnt/β-catenin signaling. Biosci Rep. 2018 Dec 7;38(6):BSR20180595.
CAS Number
– 19356-17-3
Molecular Weight
– 400.64
Compound Purity
– 99.94
SMILES
– C=C(CC1)/C(C[C@H]1O)=CC=C2[C@@]3([H])[C@@](CCC2)(C)[C@@H]([C@H](C)CCCC(C)(C)O)CC3
Clinical Information
– Launched
Research Area
– Metabolic Disease
Solubility
– DMSO : ≥ 100 mg/mL
Target
– Endogenous Metabolite;VD/VDR
Isoform
– Human Endogenous Metabolite
Pathway
– Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Product type
– Natural Products
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
