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CA-5f
$52 – $1,100
Products Details
Product Description
– CA-5f is a potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion. CA-5f increases LC3B-II (a marker to monitor autophagy) and SQSTM1 protein, and also increases ROS production. Anti-tumor activity[1].
Web ID
– HY-112698
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C24H24N2O3
References
– [1]Zhang L, et al. Identification of compound CA-5f as a novel late-stage autophagy inhibitor with potent anti-tumor effect against non-small cell lung cancer. Autophagy. 2019 Mar;15(3):391-406.
CAS Number
– 1370032-19-1
Molecular Weight
– 388.46
Compound Purity
– 99.40
SMILES
– O=C(/C(CN(C)C/1)=C/C2=CNC3=C2C=CC=C3)C1=CC4=CC=C(OC)C(OC)=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 77.5 mg/mL (ultrasonic)
Target
– Apoptosis;Autophagy
Pathway
– Apoptosis;Autophagy
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
