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117 CAD – 2,048 CADPrice range: 117 CAD through 2,048 CAD
Products Details
Product Description
– CA 074 is a potent inhibitor of cathepsin B with a Ki value of 2 to 5 nM.CA 074 inhibits ischemic hippocampal neuronal death in primates and attenuates retinopathy and optic neuritis in experimental autoimmune encephalomyelitis induced by SJL/J mice.
Web ID
– T21509
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C18H29N3O6
References
– Yamashima T, et al. Inhibition of ischaemic hippocampal neuronal death in primates with cathepsin B inhibitor CA-074: a novel strategy for neuroprotection based on ‘calpain-cathepsin hypothesis’. Eur J Neurosci. 1998 May;10(5):1723-33.
CAS Number
– 134448-10-5
Molecular Weight
– C18H29N3O6
Compound Purity
– 0.978
SMILES
– [H][C@](NC(=O)[C@H]1O[C@@H]1C(=O)NCCC)([C@@H](C)CC)C(=O)N1CCC[C@H]1C(O)=O
Pathway
– Proteases/Proteasome
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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