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Products Details
Product Description
– BX-2819 is a Hsp90 inhibitor with an IC50 value of 41 nM. BX-2819 inhibits the proliferation of cancer cells. BX-2819 can significantly inhibit the growth of NCI-N87 and HT-29 tumors in nude mice[1].
Web ID
– HY-157085
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H24N4O4S
References
– [1]Feldman RI, et al. Potent triazolothione inhibitor of heat-shock protein-90. Chem Biol Drug Des. 2009 Jul;74(1):43-50.
CAS Number
– 1184181-50-7
Molecular Weight
– 428.50
SMILES
– CCOC(NCC1=CC=C(C=C1)N2C(NN=C2C3=C(C=C(C(C(C)C)=C3)O)O)=S)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– HSP
Isoform
– HSP70;HSP90
Pathway
– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– Reference compound
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