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BuChE-IN-TM-10
$315
Only 1000 item(s) left in stock.
Products Details
Product Description
– BuChE-IN-TM-10 (TM-10) is a potent butyrylcholinesterase (BuChE) inhibitor, with an IC50 of 8.9 nM. BuChE inhibitor 1 inhibits and disaggregates self-induced Aβ aggregation, exhibiting potent antioxidant activity and good blood-brain barrier (BBB) penetration. Has potential to treat Alzheimer’s disease[1].
Web ID
– HY-114320
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C32H38N2O3
References
– [1]Sang Z, et al. Design, Synthesis, and Evaluation of Novel Ferulic Acid Derivatives as Multi-Target-Directed Ligands for the Treatment of Alzheimer’s Disease. ACS Chem Neurosci. 2019 Feb 20;10(2):1008-1024.
CAS Number
– 2313524-95-5
Molecular Weight
– 498.66
SMILES
– O=C(N1CC2=C(C=CC=C2)CC1)/C=C/C3=CC=C(OCCCCN(CC4=CC=CC=C4)CC)C(OC)=C3
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Cholinesterase (ChE)
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
