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Products Details
Product Description
– BuChE-IN-3 (Compound C4) is a potent inhibitor of BuChE with an IC50 of 8.3 nM. BuChE-IN-3 exhibits mild antioxidant capacity, nontoxicity, lipophilicity and neuroprotective activity[1].
Web ID
– HY-146686
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C21H21F2N3O4S
References
– [1]Zhang Z, et al. The structure-based optimization of δ-sultone-fused pyrazoles as selective BuChE inhibitors. Eur J Med Chem. 2020 Sep 1;201:112273.
CAS Number
– 2499488-78-5
Molecular Weight
– 449.47
SMILES
– O=S1(CCC2=C(N(N=C2CN(CC3=CC=C(C=C3)F)CCO)C4=CC=CC=C4F)O1)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Cholinesterase (ChE)
Isoform
– BChE
Pathway
– Neuronal Signaling
Product type
– Reference compound
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