Download Files:
BTYNB
Price range: 64 CAD through 949 CAD
Products Details
Product Description
– BTYNB (MDK6620) is an inhibitor of the oncofetal mRNA-binding protein IMP1 (IC50 = 5 μM for IMP1 binding to c-Myc mRNA). MDK6620 downregulates β-TrCP1 mRNA and reduces activation of nuclear transcriptional factors-kappa B (NF-κB). It disrupts this enhancer function by impairing IGF2 mRNA-binding protein 1 (IGF2BP1)-RNA association
Web ID
– T9033
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C12H9BrN2OS
References
– Mahapatra L , Andruska N , Mao C , et al. A Novel IMP1 Inhibitor, BTYNB, Targets c-Myc and Inhibits Melanoma and Ovarian Cancer Cell Proliferation[J]. Translational Oncology, 2017, 10(5):818-827.
CAS Number
– 304456-62-0
Molecular Weight
– C12H9BrN2OS
Compound Purity
– ≥95%
SMILES
– NC(=O)c1ccccc1N=Cc1ccc(Br)s1
Pathway
– Cell Cycle/Checkpoint|||NF-κB
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
Related Products
1000 in stock
1000 in stock
