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Products Details
Product Description
– BTM-3566 is an OMA1 activator. BTM-3566 activates the mitochondrial stress response. BTM-3566 induces apoptosis in diffuse large B-cell lymphomas (DLBCL) cell lines[1][2].
Web ID
– HY-155225
Shipping
– Room temperature
Molecular Formula
– C24H23F4N3O2S2
References
– [1]Schwarzer A, et al. Targeting aggressive B-cell lymphomas through pharmacological activation of the mitochondrial protease OMA1. Mol Cancer Ther. 2023 Aug 30.|[2]Adrian Schwarzer, et al. Btm-3566, a Novel Activator of the Mitochondrial Stress Response Promotes Robust Therapeutic Responses in Vitro and In Vivo in Diffuse Large B-Cell Lymphoma. Blood. Volume 138, Supplement 1, 23 November 2021, Page 684.
CAS Number
– 2228857-70-1
Molecular Weight
– 525.58
SMILES
– CC(C)SC1=C(C2=CCC(C(F)(F)F)CC2)N=C(N3N=C(C)C(C4=CC(F)=CC=C4)=C3C(O)=O)S1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Mitochondrial Metabolism
Pathway
– Apoptosis;Metabolic Enzyme/Protease
Product type
– Reference compound
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