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Products Details
Product Description
– BTK-IN-27 (example 8) is a BTK inhibitor (IC50: 0.2 nM). BTK-IN-27 shows anti-proliferative activity in TMD8 cells (IC50: < 5 nM). BTK-IN-27 can be used for research of cancer, lymphoma, leukemia and immunological diseases[1].
Web ID
– HY-156553
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C31H35N7O2
References
– [1]Mathew CALDER, et al. Pyrazolopyrimidine derivatives useful as inhibitors of bruton’s tyrosine kinase. Patent. WO2015189620.
CAS Number
– 1841502-36-0
Molecular Weight
– 537.66
SMILES
– NC1=C2C(N([C@H]3CN(CCC3)C(C=C)=O)N=C2C4=CC=C(C=C4)CNC(C5=CC=C(C=C5)C(C)(C)C)=O)=NC=N1
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Btk
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
