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Products Details
Product Description
– BTK-IN-25 (Compound 71) is a BTK inhibitor (IC50: 0.77 nM). BTK-IN-25 inhibits the proliferation of DOHH2 cells (IC50: 1 nM)[1].
Web ID
– HY-153705
Shipping
– Room temperature
Molecular Formula
– C28H27F2N3O5
References
– [1]Tan H, et al. Substituted pyrrolo[2,3-b]pyridine and pyrazolo[3,4-b]pyridine derivatives as protein kinase inhibitors and their preparation, pharmaceutical compositions and use in the treatment of cell proliferative disorders. World Intellectual Property Organization, WO2020239124 A1. 2020-12-03.|[2]Tan Haohan. Substituted pyrrolo [2,3-b ] pyridine and pyrazolo [3,4-b ] pyridine derivatives as protein kinase inhibitors. Patent. CN114008042.
CAS Number
– 2562351-92-0
Molecular Weight
– 523.53
SMILES
– O=C(C1=C(C=C(C=C1)OC2=C(C=CC=C2)F)F)C3=CNC4=NC=C(OCC)C(N[C@@H]5CC[C@H](OC5)CO)=C34
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Btk
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
