BRD5529
Add to CompareAdded to Compare

Download Files:

BRD5529

SKU T14777-2 mg Category Brand:

83 CAD

Only 1000 item(s) left in stock.

Products Details

Product Description

– BRD5529 is a selective inhibitor of CARD9-E3 ubiquitin ligase TRIM62 protein-protein interaction (IC50: 8.6 μM). BRD5529 directly and selectively binds CARD9, disrupts TRIM62 recruitment, inhibits TRIM62-mediated ubiquitinylation, and activation of CARD9.

Web ID

– T14777

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C25H31N5O4

References

– Leshchiner ES, et al. Small-molecule inhibitors directly target CARD9 and mimic its protective variant in inflammatorybowel disease. Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):11392-11397.

CAS Number

– 1358488-78-4

Molecular Weight

– C25H31N5O4

SMILES

– Cc1ccc(cc1)C(=O)Nc1cnc(N2CCC(CC2)(N2CCCCC2)C(N)=O)c(c1)C(O)=O

Target

– Others

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

Related Products

Select options
Iron(II) fumarate
Iron(II) fumarate Price range: 48 CAD through 128 CAD
1 g10 g5 g

1000 in stock

Select options
Phenytoin sodium
Phenytoin sodium Price range: 72 CAD through 85 CAD
1 g1 mL * 10 mM (in DMSO)500 mg

1000 in stock

Select options
2,2'-Bipyridine
2,2′-Bipyridine Price range: 46 CAD through 171 CAD
1 g100 mg500 mg

1000 in stock

Select options
4-Methoxycoumarine
4-Methoxycoumarine Price range: 56 CAD through 266 CAD
1 g1 mL * 10 mM (in DMSO)50 mg

1000 in stock

Select options
4-Hydroxy-6-methylcoumarin
4-Hydroxy-6-methylcoumarin Price range: 46 CAD through 78 CAD
1 mL * 10 mM (in DMSO)500 mg

1000 in stock

My Cart
Wishlist
Recently Viewed
Categories

Request Data Sheet / Safty Data Sheet

Please enable JavaScript in your browser to complete this form.
=

Price Request

Please enable JavaScript in your browser to complete this form.
=

Compare Products (0 Products)
document.addEventListener('elementor/popup/show', function() { if (typeof turnstile !== 'undefined') { document.querySelectorAll('.cf-turnstile').forEach(function(el) { if (!el.dataset.rendered) { turnstile.render(el); el.dataset.rendered = true; } }); } });