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Products Details
Product Description
– BRD4 Inhibitor-16 (Compound 4) is a potent inhibitor of bromodomain 4 (BRD4). Overexpression of bromodomain 4 (BRD4) is closely correlated with a variety of human cancers by regulating the histone post-translational modifications. BRD4 Inhibitor-16 represents a useful tool for explorative studies of BRD4 inhibition, such as an improved understanding of BRD4 inhibitor release-related information[1].
Web ID
– HY-115926
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C42H43N7O8S
References
– [1]Zhang H, et al. Activatable fluorescence molecular imaging and anti-tumor effects investigation of GSH-sensitive BRD4 ligands [published online ahead of print, 2022 Jan 25]. Bioorg Chem. 2022;120:105636.
Molecular Weight
– 805.90
SMILES
– CC1=NOC(C)=C1C2=CC=C3C(C(N(C(N3C)=O)CC(NCCNS(=O)(C4=C5C=CC=C6C(N(C(C(C=C4)=C65)=O)CCN7CCOCC7)=O)=O)=O)C8=CC=CC=C8)=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Epigenetic Reader Domain
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
