BRD0705
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BRD0705

SKU T10606-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 146 CAD through 1,248 CAD

Products Details

Product Description

– BRD0705 is a potent, orally active GSK3α inhibitor with high selectivity (IC50: 66 nM; Kd: 4.8 μM), demonstrating an 8-fold higher selectivity for GSK3α compared to GSK3β (IC50: 515 nM).

Web ID

– T10606

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H23N3O

References

– Wagner FF, et al. Exploiting an Asp-Glu “switch” in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia. Sci Transl Med. 2018 Mar 7;10(431). pii: eaam8460.

CAS Number

– 2056261-41-5

Molecular Weight

– C20H23N3O

Compound Purity

– 0.9959

SMILES

– CC[C@@]1(C2=CNNC2=NC2=C1C(=O)CC(C)(C)C2)c1ccccc1

Target

– Others

Pathway

– PI3K/Akt/mTOR signaling|||Stem Cells

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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