BR351

SKU T10597-25 mg Category Brand:

Price range: 2,672 CAD through 4,480 CAD

Products Details

Product Description

– BR351 is a brain-penetrant MMP inhibitor with IC50 values of 4 nM for MMP2, 2 nM for MMP8, 11 nM for MMP9, and 50 nM for MMP13.

Web ID

– T10597

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H25FN2O5S

References

– Wagner S, et al. Novel fluorinated derivatives of the broad-spectrum MMP inhibitors N-hydroxy-2(R)-[[(4-methoxyphenyl)sulfonyl](benzyl)- and (3-picolyl)-amino]-3-methyl-butanamide as potential tools for the molecular imaging of activated MMPs with PET. J Med Chem. 2007 Nov 15;50(23):5752-64.

CAS Number

– 960113-85-3

Molecular Weight

– C20H25FN2O5S

SMILES

– N([C@@H](C(NO)=O)C(C)C)(S(=O)(=O)C1=CC=C(OCCF)C=C1)CC2=CC=CC=C2

Target

– Raf|||AChR

Pathway

– Proteases/Proteasome

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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