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Br-PBTC
1,552 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– Br-PBTC is a highly potent, 2/4 subtype-selective positive allosteric modulator of nicotinic acetylcholine receptors (nAChRs). It specifically targets α2β2, α2β4, α4β2, α4β4, (α4β2)2α4, and (α4β2)2β2 subtypes of nAChRs, with EC50 values ranging from 0.1 to 0.6 μM. Br-PBTC exerts its activity by binding to the c-tail region of an α subunit.
Web ID
– T39286
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C14H15BrN2OS
References
– Wang J, et al. A Novel α2/α4 Subtype-selective Positive Allosteric Modulator of Nicotinic Acetylcholine Receptors Acting from the C-tail of an α Subunit. J Biol Chem. 2015;290(48):28834-28846.
CAS Number
– 1839519-57-1
Molecular Weight
– C14H15BrN2OS
SMILES
– Brc1cccc2cc(sc12)C(=O)N[C@@H]1CCCNC1
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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