BPHA

SKU T36712-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 286 CAD through 4,128 CAD

Products Details

Product Description

– BPHA (MMP-2/MMP-9 Inhibitor II) is a potent, selective and orally active inhibitor of MMP-2, MMP-9 and MMP-14 with IC50s of 12 nM, 16 nM and 17 nM, respectively.BPHA does not inhibit MMP-1, -3 and -7 (IC50s of 974, >1000 and 795 nM, respectively).BPHA has anti-angiogenic and BPHA has anti-angiogenic and anti-tumor activities.

Web ID

– T36712

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H20N2O4S

References

– Maekawa R, et al. Correlation of antiangiogenic and antitumor efficacy of N-biphenyl sulfonyl-phenylalanine hydroxiamic acid (BPHA), an orally-active, selective matrix metalloproteinase inhibitor. Cancer Res. 1999;59(6):1231-1235.

CAS Number

– 193807-60-2

Molecular Weight

– C21H20N2O4S

Compound Purity

– 0.9972

SMILES

– S(N[C@H](CC1=CC=CC=C1)C(NO)=O)(=O)(=O)C2=CC=C(C=C2)C3=CC=CC=C3

Pathway

– Proteases/Proteasome

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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